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Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
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NB-598 Maleate is a small-molecule inhibitor targeting squalene epoxidase (SE) an essential enzyme in cholesterol biosynthesis It is designed to inhibit SE thereby disrupting the oxygenation of squalene and affecting downstream synthesis of cholesterol intermediates particularly within farnesol-dependent pathways leading to triglyceride biosynthesis NB-598 Maleate exerts its biological activity primarily through inhibition of squalene epoxidase In mouse pancreatic islet models NB-598 Maleate reduces insulin secretion under both basal and glucose-stimulated conditions Additionally this compound inhibits calcium voltage-dependent (CaV) ion channels in cellular assays Based on these pharmacological properties NB-598 Maleate holds research potential in studying cholesterol biosynthesis pathways lipid metabolism insulin regulation and the physiological role of CaV channels
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(S)-Timolol Maleate (L-714,465 Maleate) is a non-cardioselective hydrophilic β-adrenoceptor blocker. It is widely used as a standard medication for intraocular pressure (glaucoma) by preventing the production of aqueous humor. This compound can also be used for hypertension, angina pectoris, and myocardial infarction.
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Taurocholic acid (Sodium taurocholate hydrate) a bile salt formed in the liver is the product of conjugation of cholic acid with taurine that is involved in the emulsification of lipids Its sodium salt is the chief ingredient of the bile of carnivorous animals Taurocholic acid sodium salt hydrate can be used to induce animal models of Severe Acute Pancreatitis (SAP)
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Zetomipzomib maleate is a selective immunoproteasome inhibitor (KZR-616 maleate) used as a research reagent to study autoimmune and inflammatory pathways. It is supplied as a small, research-scale sample suitable for in vitro and preclinical work.
Selective inhibitor of immunoproteasome subunits LMP7 and LMP2.
Suitable for preclinical research and mechanistic studies.
Provided as a low-amount research sample for laboratory use.
Stored and handled according to reagent safety protocols and SDS guidance.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More